Ke is an Associate Professor in the Department of Molecular Biomedical Sciences at the College of Veterinary Medicine and an Associate Professor in the UNC/NCSU joint Department of Biomedical Engineering. He is also an adjunct associate professor at the UNC Eshelman School of Pharmacy and UNC School of Medicine. He directs the BioTherapeutics Lab which focuses on stem cells, biomaterials, and nanomedicine. Prior to this position, Ke was an Assistant Professor at Cedars-Sinai Medical Center and University of California Los Angeles School of Medicine, where his research focused on stem cells and regenerative medicine in animal models. Ke also served as the director of the stem cell lab for multiple clinical trials including a clinical trial using patient's own cardiac stem cells to treat heart attack. Ke's formal education began with a B.S. in Pharmaceutical Engineering from the Zhejiang University, followed by a Ph.D. degree in Biological Engineering from University of Georgia. AffiliationsNCSU Faculty Cluster: Translational Regenerative Medicine

(2015) Adult Lung Spheroid Cells Contain Progenitor Cells and Mediate Regeneration in Rodents with Bleomycin-Induced Pulmonary Fibrosis(2015) Intravenous administration of cardiac progenitor cell-derived exosomes mediates heart regeneration after doxorubicin-induced dilated cardiomyopathy(2015) Cellular post-conditioning: allogeneic cardiosphere-derived cells reduce infarct size and attenuate microvascular obstruction when administered after reperfusion in pigs with acute myocardial infarction(2015) Cryoperservation of cardiomyocytes for cell-based assay(2015) Regenerative potential of canine cardiac stem cells(2015) Cryopreservation of Cardiomyocytes(2014) Intracoronary cardiosphere-derived cells after myocardial daikin air conditioning units australiainfarction: evidence of therapeutic regeneration in the final 1-year results of the CADUCEUS trial (CArdiosphere-Derived aUtologous stem CElls to reverse ventricUlar dySfunction).goodman ac unit wholesale

(2014) Human cardiosphere-derived cells from advanced heart failure patients exhibit augmented functional potency in a mouse model of myocardial infarction(2014) Therapeutic efficacy of cardiosphere-derived cells in a transgenic mouse model of nonischemic dilated cardiomyopathy(2014) Exosomes as critical agents of cardiac regeneration triggered by cell therapy(2014) Cardiosphere-derived Cells Stimulate Cardiomyocyte Proliferation via β1 Integrin Signaling(2014) Magnetic antibody-linked nanomatchmakers for therapeutic cell targeting(2014) CD90/Thy-1-negative cardiosphere-derived cells exhibit augmented regenerative potency in humans and mice with myocardial air conditioning unit dysoninfarction(2014) et al Allogeneic Cardiospheres Delivered via Percutaneous Transendocardial Injection Increase Viable Myocardium, Decrease Scar Size, and Attenuate Cardiac Dilatation in Porcine Ischemic Cardiomyopathy(2014) Engineered biological wire restores electrical conduction in complete heart block(2014) Magnetic targeting of cardiosphere-derived stem cells with ferumoxytol nanoparticles for treating rats with myocardial infarction(2013) Validation of contrast-enhanced MRI to monitor regenerative efficacy after cell therapy in a porcine model of convalescent myocardial infarction(2013) Cardiomyocyte proliferation and progenitor cell recruitment underlie

therapeutic regeneration after myocardial infarction in the adult mouse heart(2012) Transplantation of platelet gel spiked with cardiosphere-derived cells boosts structural and functional benefits relative to gel transplantation alone in rats with myocardial infarction(2012) Intramyocardial injection of platelet gel promotes endogenous repair and augments cardiac function in rats with myocardial infarction(2012) Three Dimensional Neuronal Cell Cultures More Accurately Model Voltage Gated Calcium Channel Functionality in Freshly Dissected Nerve Tissue(2012) Direct comparison of different stem cell types and subpopulations reveals superior paracrine potency and myocardial repair efficacy with cardiosphere-derived cells(2012) Mechanism of extravasation of infused regenerative cells from microvessels into tissue parenchyma(2012) Dose-dependent functional benefit of human cardiosphere transplantation in mice with acute myocardial infarction(2012) Functional performance of human cardiosphere-derived cells delivered in an in situ polymerizable hyaluronan-gelatin hydrogel(2012) Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS)

: a prospective, randomised phase 1 trial(2011) Safety and efficacy of allogeneic cell therapy in infarcted rats transplanted with mismatched(2011) Neural Cell 3D Microtissue Formation Is Marked by Cytokines’ Up-Regulation(2011) The amelioration of cardiac dysfunction after myocardial infarction by the injection of keratin biomaterials derived from human hairThe CADUCEUS (CArdiosphere-Derived aUtologous Stem CElls to Reverse ventricUlar dySfunction) Trial(2010) Dedifferentiation and Proliferation of Mammalian Cardiomyocytes(2010) Exploring cellular adhesion and differentiation in a micro-/nano-hybrid polymer scaffold(2010) Magnetic targeting enhances engraftment and functional benefit of iron-labeled cardiosphere-derived cells in myocardial infarction(2010) Cardiospheres recapitulate a niche-like microenvironment rich in stemness and cell-matrix interactions, rationalizing their enhanced functional potency for myocardial repair(2010) Expansion of human cardiac stem cells in physiological low oxygen improves cell production efficiency and potency for myocardial repairHeart to heart: Elusive mechanism of cell therapy(2009) Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue(2008) Three dimensional scaffolds for

high throughput cell-based assay systemsTaking Cell Culture in Drug Discovery to the Third Dimension-A Patent ReviewENStem-A human neural progenitors cultured in 3D polystyrene scaffolds for high physiological relevance(2003) Application potentials of on-line near infrared spectroscopy technology in manufacturing of traditional chinese medicine New Way Out: Researchers Show How Stem Cells Exit BloodstreamSpheroid Stem Cell Production Sows Hope for IPF TreatmentHeart of the Matter: Veterinary Research and America's Heart Disease BurdenNew Nanomedicine Improves Stem Cell Therapy, May Help Regenerate Healthy Heart TissueA Conversation with Ke Cheng, NC State University Professor of Regenerative MedicineResearcher Repairs Damaged Heart Tissue with Adult Stem CellsStem cell therapy is a promising option for repairing heart tissue damaged by heart attack. However, the main obstacle to cardiac stem cell therapy also happens to be pretty difficult to get around – and that’s the fact that the heart is constantly in motion.